146897-68-9
146897-68-9 結(jié)構(gòu)式
基本信息
乳鐵蛋白B
FF-25
乳鐵蛋白 人
乳鐵傳遞蛋白
乳鐵蛋白,牛來(lái)源
乳鐵蛋白單克隆抗體
乳鐵蛋白 來(lái)源于牛奶
乳鐵蛋白 來(lái)源于人奶
乳鐵蛋白B/乳鐵蛋白
COLOSTRUM
AIDS096157
Lactoferricin
Lactoferricin B
Lactoferrin 90%+
Lactoferricin B25
LACTOFERRIN, HUMAN
LACTOFERRIN (BOVINE)
LACTOFERRIN, HUMAN MILK
物理化學(xué)性質(zhì)
常見(jiàn)問(wèn)題列表
乳鐵蛋白廣泛分布于人和哺乳動(dòng)物乳汁和其他多種組織及其分泌液中（包括淚液、精液、膽汁、滑膜液等內(nèi)、外分泌液和嗜中性粒細(xì)胞），但乳汁中含量較高，其中牛初乳中乳鐵蛋白含量最高。血液中乳鐵蛋白主要由多核細(xì)胞分泌，骨髓、唾液腺及子宮內(nèi)膜等也能分泌少量乳鐵蛋白。
乳鐵蛋白來(lái)源于人奶的廣泛生物學(xué)功能決定了其在化妝品、食品、動(dòng)物生產(chǎn)、醫(yī)療等領(lǐng)域中的應(yīng)用，可作為抗氧化劑、免疫促進(jìn)劑、補(bǔ)鐵劑、藥物載體等。
Lactoferrin 17-41 (Lactoferricin B) has an MIC of 30 μg/ml against
E. coli
ATCC 25922.
Lactoferrin 17-41 significantly stimulates apoptosis of HT-29 cells and displays cytotoxic activity on HT-29 cells.
Lactoferrin 17-41 variously regulats transcription of genes involved in the p53 signaling pathway, such as PMAIP-1, TP5313, and SFN.
Lactoferrin 17-41 can bind LPS from Gram-negative bacteria and that it can inhibit LPS induced cytokine response in human monocytic cells.
Cell Viability Assay
| Cell Line: | HT-29 cells |
| Concentration: | 50, 100, 200, 400, 800 or 1000 μg/mL |
| Incubation Time: | 4, 12, 24 or 48 hours |
| Result: | More effective at inducing apoptosis at 400 μg/mL. Higher toxicity is shown at 800 μg/mL. |