145916-41-2
中文名稱
Propargyl-PEG2-Tos
英文名稱
Propargyl-PEG2-Tos
CAS
145916-41-2
分子式
C12H14O4S
分子量
254.3
MOL 文件
145916-41-2.mol
更新日期
2024/10/27 20:45:59
145916-41-2 結(jié)構(gòu)式
基本信息
中文別名
丙炔-三聚乙二醇-對(duì)甲苯磺酸酯2-(丙-2-炔-1-基氧基)乙基 4-甲基苯磺酸酯
英文別名
Propargyl-PEG2-Tos2-(prop-2-yn-1-yloxy)ethyl 4-methylbenzenesulfonate
Ethanol, 2-(2-propyn-1-yloxy)-, 1-(4-methylbenzenesulfonate)
應(yīng)用領(lǐng)域
用途一
Propargyl-PEG2-Tos is a PEG linker containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.