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144-90-1

中文名稱 3-氨基異丁酸
英文名稱 DL-3-AMINOISOBUTYRIC ACID
CAS 144-90-1
分子式 NH2CH2CH(CH3)COOH
分子量 103.12
MOL 文件 144-90-1.mol
更新日期 2024/10/28 09:48:11
144-90-1 結(jié)構(gòu)式 144-90-1 結(jié)構(gòu)式

基本信息

中文別名
Α-甲基-Β-丙氨酸
3-氨基-2-甲基丙酸
英文別名
Methylalanine
3-aminoisobutyric ac
DL-BETA-AMINOISOBUTYRIC ACID
2-(aminomethyl)propanoic acid
DL-3-AMinoisobutyric acid 98%
3-amino-2-methylpropanoic acid
2-Methyl-3-aminopropionic acid
2-Methyl-3-aminopropanoic acid
3-azanyl-2-methyl-propanoic acid
DL-3-Aminoisobutyric Acid Hydrate>
所屬類別
生物化工:其他氨基酸衍生物

物理化學(xué)性質(zhì)

熔點(diǎn)246.72°C (estimate)
沸點(diǎn)223.6±23.0 °C(Predicted)
密度1.2300 (estimate)
折射率1.4650 (estimate)
儲(chǔ)存條件Keep in dark place,Inert atmosphere,Room temperature
溶解度少許溶于甲醇和水
酸度系數(shù)(pKa)3.69±0.16(Predicted)
形態(tài)粉末晶體
顏色白色
BRN1720958
InChIInChI=1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7)
InChIKeyQCHPKSFMDHPSNR-UHFFFAOYSA-N
SMILESC(O)(=O)C(C)CN

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H315-H319-H335
WGK Germany3
RTECS號(hào)UA2430000
海關(guān)編碼2922.49.4950

常見問題列表

生物活性
3-Aminoisobutyric acid (3-Amino-2-methylpropanoic acid, 3-Aminoisobutyrate, β-aminoisobutyric acid)是胸腺嘧啶的代謝產(chǎn)物。
靶點(diǎn)

Human Endogenous Metabolite

體內(nèi)研究

Weight is slightly decreased in the mice by the end of 3-Amino-2-methylpropanoic acid (BAIBA) treatment. Analysis of body composition using MRI demonstrates BAIBA treatment significantly decreases body fat in the mice. Consistent with the effects on thermogenic and β-oxidation gene expression and body weights, analysis with metabolic cages indicates that oxygen consumption (VO2) and whole body energy expenditure are increased in the BAIBA treated mice without any significant difference in activity or food intake. The mice are also challenged with an intraperitoneal glucose tolerance test (IPGTT). BAIBA is found to significantly improve the glucose tolerance in the mice as determined by the area under the curve of the IPGTT.

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