144-90-1
基本信息
3-氨基-2-甲基丙酸
3-aminoisobutyric ac
DL-BETA-AMINOISOBUTYRIC ACID
2-(aminomethyl)propanoic acid
DL-3-AMinoisobutyric acid 98%
3-amino-2-methylpropanoic acid
2-Methyl-3-aminopropionic acid
2-Methyl-3-aminopropanoic acid
3-azanyl-2-methyl-propanoic acid
DL-3-Aminoisobutyric Acid Hydrate>
物理化學(xué)性質(zhì)
常見問題列表
Human Endogenous Metabolite
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Weight is slightly decreased in the mice by the end of 3-Amino-2-methylpropanoic acid (BAIBA) treatment. Analysis of body composition using MRI demonstrates BAIBA treatment significantly decreases body fat in the mice. Consistent with the effects on thermogenic and β-oxidation gene expression and body weights, analysis with metabolic cages indicates that oxygen consumption (VO2) and whole body energy expenditure are increased in the BAIBA treated mice without any significant difference in activity or food intake. The mice are also challenged with an intraperitoneal glucose tolerance test (IPGTT). BAIBA is found to significantly improve the glucose tolerance in the mice as determined by the area under the curve of the IPGTT.