1426164-52-4
中文名稱
馬來(lái)酰亞胺-酰胺-PEG2-酸
英文名稱
Bis-Mal-Lysine-PEG4-acid
CAS
1426164-52-4
分子式
C31H45N5O13
分子量
695.71
MOL 文件
1426164-52-4.mol
1426164-52-4 結(jié)構(gòu)式
基本信息
中文別名
馬來(lái)酰亞胺-酰胺-PEG2-酸雙馬來(lái)酰亞胺-賴氨酸-四聚乙二醇-羧酸
英文別名
Bis-Mal-Lysine-PEG4-acid4,7,10,13-Tetraoxa-16,23-diazahexacosanoic acid, 26-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-18-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]-17,24-dioxo-, (18S)-
應(yīng)用領(lǐng)域
用途一
Bis-Mal-Lysine-PEG4-acid is a PEG linker with two maleimide groups which can react with thiols from pH ranges of 6.5 to 7.5 to from a thiolester bond. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.