1399767-47-5
中文名稱(chēng)
化合物 T28604
英文名稱(chēng)
RO-5464466
CAS
1399767-47-5
分子式
C16H26N2O3S
分子量
326.46
MOL 文件
1399767-47-5.mol
1399767-47-5 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
RO5464466 is an inhibitor of influenza A virus (H1N1) fusion. RO5464466 targeted HA. In cell-based assays involving multiple rounds of virus infection and replication, RO5464466 inhibited an established influenza infection. The overall production of progeny viruses, as a result of the compound's inhibitory effect on fusion, was dramatically reduced by 8 log units when compared with a negative control. Furthermore, RO5487624, a close analogue of