S 14671 N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]thiophene-2-carboxamide N-[2-[4-(7-Methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]-2-thiophenecarboxamide 2-Thiophenecarboxamide, N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]-
應(yīng)用領(lǐng)域
用途一
S-14671 is a 5-HT1A receptor agonist (pKi = 9.3) with high efficacy and exceptional in vivo potency, and also as a 5-HT2A and 5-HT2C receptor antagonist (both are pKi = 7.8). It displays only low and non-significant affinity for 5-HT1B and 5-HT3 sites.