1354030-51-5
中文名稱
5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
英文名稱
5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
CAS
1354030-51-5
分子式
C21H22Cl2N2OS
分子量
421.383
MOL 文件
1354030-51-5.mol
1354030-51-5 結(jié)構(gòu)式
基本信息
中文別名
化合物 T29065 英文別名
UNC9994UNC-9994
UNC 9994
5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
應(yīng)用領(lǐng)域
用途一
UNC9994 is a β-arrestin-biased dopamine D? receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%). UNC9994 has robust in vivo antipsychotic drug-like activities. Functionally selective G protein-coupled receptor (GPCR) ligands, which differentially modulate canonical and noncanonical signaling, are extremely useful for elucidating key signal transduction pathways essential for both the therapeutic actions and side effects of drugs.