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132996-61-3

中文名稱 成骨生長肽
英文名稱 OSTEOGENIC GROWTH PEPTIDE
CAS 132996-61-3
分子式 C68H110N22O18
分子量 1523.74
MOL 文件 132996-61-3.mol
更新日期 2025/01/10 21:28:03
132996-61-3 結(jié)構(gòu)式 132996-61-3 結(jié)構(gòu)式

基本信息

中文別名
成骨生長肽
L-丙氨酰-L-亮氨酰-L-賴氨酰-L-精氨酰-L-谷氨酰甘氨酰-L-精氨酰-L-蘇氨酰-L-亮氨酰-L-酪氨酰甘氨酰-L-苯丙氨酰甘氨酰-甘氨酸
英文別名
Osteogenic Growth Peptide OGP
OSTEOGENIC GROWTH PEPTIDE USP/EP/BP
Glycine, L-alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-threonyl-L-leucyl-L-tyrosylglycyl-L-phenylalanylglycyl-
D-Alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-allothreonyl-L-leucyl-D-tyrosylglycyl-N-benzylglycylglycylglycinamide
所屬類別
生物化工:多肽

物理化學性質(zhì)

儲存條件−20°C
形態(tài)Solid
顏色White to off-white
成骨生長肽價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2024/11/08HY-P1563成骨生長肽
Osteogenic Growth Peptide, OGP
132996-61-31mg950元
2024/11/08HY-P1563成骨生長肽
Osteogenic Growth Peptide, OGP
132996-61-35mg3900元
2024/08/19HY-P1563成骨生長肽
Osteogenic Growth Peptide, OGP
132996-61-310mg6300元

常見問題列表

生物活性
Osteogenic Growth Peptide, OGP 是由 14 個氨基酸殘基組成的多肽,是一種對骨髓損傷有系統(tǒng)性應答的促進因子,以 μM 級濃度存在于哺乳動物的血清中。
體外研究

Osteogenic Growth Peptide (OGP) regulates proliferation, differentiation, and matrix mineralization in osteoblast lineage cells. The active portion of OGP, the OGP(10-14) region, is cleaved from the peptide and binds to the OGP receptor which activates the MAP kinase, the Src, and the RhoA pathways. Osteogenic Growth Peptide (OGP) is a native molecule with a primary structure identical to the C-terminus of histone H4, whose sequence contains a highly conserved 14-amino acid motif (NH 2 -ALKRQGRTLYGFGG-OH). This peptide is isolated from blood during osteogenic remodeling of post-ablation of marrow regeneration. The osteogenic growth peptide (OGP) and its C-terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of osteoblastic lineage cells.

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