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132996-61-3

中文名稱 成骨生長(zhǎng)肽
英文名稱 OSTEOGENIC GROWTH PEPTIDE
CAS 132996-61-3
分子式 C68H110N22O18
分子量 1523.74
MOL 文件 132996-61-3.mol
更新日期 2024/11/03 16:22:41
132996-61-3 結(jié)構(gòu)式 132996-61-3 結(jié)構(gòu)式

基本信息

中文別名
成骨生長(zhǎng)肽
L-丙氨酰-L-亮氨酰-L-賴氨酰-L-精氨酰-L-谷氨酰甘氨酰-L-精氨酰-L-蘇氨酰-L-亮氨酰-L-酪氨酰甘氨酰-L-苯丙氨酰甘氨酰-甘氨酸
英文別名
Osteogenic Growth Peptide OGP
OSTEOGENIC GROWTH PEPTIDE USP/EP/BP
Glycine, L-alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-threonyl-L-leucyl-L-tyrosylglycyl-L-phenylalanylglycyl-
D-Alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-allothreonyl-L-leucyl-D-tyrosylglycyl-N-benzylglycylglycylglycinamide
所屬類別
生物化工:多肽

物理化學(xué)性質(zhì)

儲(chǔ)存條件−20°C
形態(tài)Solid
顏色White to off-white
成骨生長(zhǎng)肽價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/08/19HY-P1563成骨生長(zhǎng)肽
Osteogenic Growth Peptide, OGP
132996-61-31mg950元
2024/08/19HY-P1563成骨生長(zhǎng)肽
Osteogenic Growth Peptide, OGP
132996-61-35mg3900元
2024/08/19HY-P1563成骨生長(zhǎng)肽
Osteogenic Growth Peptide, OGP
132996-61-310mg6300元

常見問題列表

生物活性
Osteogenic Growth Peptide, OGP 是由 14 個(gè)氨基酸殘基組成的多肽,是一種對(duì)骨髓損傷有系統(tǒng)性應(yīng)答的促進(jìn)因子,以 μM 級(jí)濃度存在于哺乳動(dòng)物的血清中。
體外研究

Osteogenic Growth Peptide (OGP) regulates proliferation, differentiation, and matrix mineralization in osteoblast lineage cells. The active portion of OGP, the OGP(10-14) region, is cleaved from the peptide and binds to the OGP receptor which activates the MAP kinase, the Src, and the RhoA pathways. Osteogenic Growth Peptide (OGP) is a native molecule with a primary structure identical to the C-terminus of histone H4, whose sequence contains a highly conserved 14-amino acid motif (NH 2 -ALKRQGRTLYGFGG-OH). This peptide is isolated from blood during osteogenic remodeling of post-ablation of marrow regeneration. The osteogenic growth peptide (OGP) and its C-terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of osteoblastic lineage cells.

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