120602-99-5
中文名稱(chēng)
NC 190
英文名稱(chēng)
NC 190
CAS
120602-99-5
分子式
C23H21N4O5.Na
分子量
456.432
MOL 文件
120602-99-5.mol
120602-99-5 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
NC190 is a topoisomerase II-inhibitor that inhibited the growth of FM3A cells in clinical trials. NC-190 strongly inhibited the growth of FM3A cells with an IC50 of 0.019 microg/ml (0.042 microM) when cultured with NC-190 for 48 h. NC-190 potently suppressed DNA synthesis, with 90% inhibition observed at 0.1 microg/ml of NC-190.