1187479-72-6
中文名稱
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
英文名稱
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
CAS
1187479-72-6
分子式
C29H45BN2O5
分子量
512.49
MOL 文件
1187479-72-6.mol
1187479-72-6 結(jié)構(gòu)式
基本信息
中文別名
硼替佐米雜質(zhì)59 英文別名
Bortezomib Impurity 53(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate
所屬類別
分析化學：藥典標準品和雜質(zhì)標準品應(yīng)用領(lǐng)域
用途一
N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of bortezomib (B675700).Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.