1034863-51-8
中文名稱
RB-OPD
英文名稱
Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 2-(2-aminophenyl)-3',6'-bis(diethylamino)-
CAS
1034863-51-8
分子式
C34H36N4O2
分子量
532.68
MOL 文件
1034863-51-8.mol
更新日期
2023/03/20 15:41:21
1034863-51-8 結構式
基本信息
中文別名
一氧化氮(NO)熒光探針 英文別名
RB-OPDNO-red
2-(2-aminophenyl)-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one
2-(2-aminophenyl)-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one
Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 2-(2-aminophenyl)-3',6'-bis(diethylamino)-
物理化學性質
熔點178-179 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
沸點724.0±60.0 °C(Predicted)
密度1.28±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)6.26±0.20(Predicted)
形態(tài)Solid
顏色Off-white to light yellow
常見問題列表
生物活性
RB-OPD (NO-red) 是鄰苯二胺 (OPD) 型的一氧化氮 (NO) 熒光探針，具有很高的靈敏度和選擇性 (λex=550 nm, λem=590 nm)。體外研究
RB-OPD (compound 1) exhibits “turn-on” type fluorogenic and chromogenic behavior toward NO in aqueous solution with great sensitivity and selectivity, and it can be used for the sensing of NO under normal physiological conditions. NO-red is composed of two moieties: rhodamine B spirolactam as the potential strong fluorophore and chromophore, and o-phenylenediamine as an NO-reactive group in a lactam form as a “masked” NO-sensitive modulator.