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ChemicalBook--->CAS DataBase List--->99026-77-4

99026-77-4

99026-77-4 Structure

99026-77-4 Structure
IdentificationBack Directory
[Name]

GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA
[CAS]

99026-77-4
[Synonyms]

[ALA107]-MBP (104-118)
[ALA107]-MBP FRAGMENT 104-118
[Ala107]-Myelin Basic Protein (104-118)
[ALA107]-MYELIN BASIC PROTEIN FRAGMENT 104-118
GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA
L-Alanine, glycyl-L-lysylglycyl-L-alanylglycyl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-arginyl-L-phenylalanyl-L-seryl-L-tryptophylglycyl- (9CI)
(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[(2-aminoacetyl)amino]hexanoyl]amino]acetyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]propanoic acid
[Molecular Formula]

C67H104N20O19
[MDL Number]

MFCD00273540
[MOL File]

99026-77-4.mol
[Molecular Weight]

1493.67
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

Soluble to 1 mg/ml in 10% acetonitrile
[form ]

solid
[color ]

White
[Sequence]

H-Gly-Lys-Gly-Ala-Gly-Leu-Ser-Leu-Ser-Arg-Phe-Ser-Trp-Gly-Ala-OH
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Biological Activity]

[ala107]-mbp (104-118) is a non-competitive inhibitor of pkc and synthetic peptide analog of bovine myelin basic protein (mbp) with ic50 value of 46 - 145 mm.1. substrate specificity of phospholipid/ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. turner et al. j.biol.chem., 1985;260:115032. synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase c). su et al. biochem.biophys.res.commun., 1986;134:78
[Biochem/physiol Actions]

[Ala107]-Myelin Basic Protein Fragment 104-118 is an inhibitor of protein kinase C.
[storage]

Desiccate at -20°C
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