| Identification | Back Directory | [Name]
4-(4-(DIMETHYLAMINO)STYRYL)-N-METHYLPYRIDINIUM IODIDE | [CAS]
959-81-9 | [Synonyms]
D 288
Daspi
DASPMI
4-DI-1-ASP
AURORA 18081
4-DI-1-ASP IODIDE
4-Di-1-ASP [DASPMI]
40-dimethylamino-1-methylstilbazolium Iodide
4'-DIMETHYLAMINO-N-METHYL-4-STILBAZOLIUM IODIDE
40-dimethylamino-
n-methyl-4-stilbazolium Iodide
1-METHYL-4-P-DIMETHYLAMINO-STYRYL-PYRIDINIUM-IODIDE
W-(N'-METHYLPYRIDYL-4')-4-DIMETHYLAMINOSTYRENE IODIDE
4-[P-(DIMETHYLAMINO)STYRYL]-1-METHYLPYRIDINIUM IODIDE
4-[4-(DIMETHYLAMINO)STYRYL]-1-METHYLPYRIDINIUM IODIDE
4-(4-(DIMETHYLAMINO)STYRYL)-N-METHYLPYRIDINIUM IODIDE
W-(n0-methylpyridyl-
40)-4-dimethylaminostyrene Iodide
4-[4-(DIMETHYLAMINO)-A-STYRYL]-1-METHYLPYRIDINIUM IODIDE
PYRIDINIUM, 4-[P-(DIMETHYLAMINO)STYRYL]-1-METHYL-, IODIDE
(E)-4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide
TRANS-4-[4-(DIMETHYLAMINO)STYRYL]-1-METHYLPYRIDINIUM IODIDE
4-[2-[4-(DIMETHYLAMINO)PHENYL]ETHENYL]-1-METHYLPYRIDINIUM IODIDE
4-[(E)2-[4-(DIMETHYLAMINO)PHENYL]VINYL]-1-METHYLPYRIDINIUM IODIDE
PYRIDINIUM, 4-[2-[4-(DIMETHYLAMINO)PHENYL]ETHENYL]-1-METHYL-, IODIDE | [Molecular Formula]
C16H19IN2 | [MDL Number]
MFCD00031907 | [MOL File]
959-81-9.mol | [Molecular Weight]
366.24 |
| Chemical Properties | Back Directory | [Melting point ]
261–262℃ | [solubility ]
Soluble in methanol, N,N-dimethylformamide | [form ]
Solid | [color ]
Greenish purple solid;2 Purple solid;
Red needles | [λmax]
475 nm | [Biological Applications]
Detecting nucleic acids,prostate cancer; treating amyloidosis disorders,bacterial infection | [Major Application]
Electrochromic materials;glass;nonlinear optical (NLO) materials;photoconductors;thin films |
| Hazard Information | Back Directory | [Uses]
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λex /λem = 475/606 nm) [1][2]. | [Definition]
ChEBI:4-[4-(dimethylamino)styryl]-N-methylpyridinium iodide is an organic iodide salt consisting of pyridinium iodide having a methyl substituent at the 1-position and a 4-dimethylaminostyryl substituent at the 4-position. It has a role as a fluorochrome. It is an organic iodide salt and a pyridinium salt. It contains a 4-[4-(dimethylamino)styryl]-N-methylpyridinium. | [References]
[1] Lilia Y Kucheryavykh, et al. Visualization of implanted GL261 glioma cells in living mouse brain slices using fluorescent 4-(4-(dimethylamino)-styryl)-N-methylpyridinium iodide (ASP+). Biotechniques. 2012 Nov;53(5):305-9. DOI:10.2144/000113940
[2] Jensen J H Wong, et al. Simultaneous High-Throughput Conformational and Colloidal Stability Screening Using a Fluorescent Molecular Rotor Dye, 4-(4-(Dimethylamino)styryl)-N-Methylpyridinium Iodide (DASPMI). J Biomol Screen. 2016 Sep;21(8):842-50. DOI:10.1177/1087057116646553 |
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