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ChemicalBook--->CAS DataBase List--->94885-04-8

94885-04-8

94885-04-8 Structure

94885-04-8 Structure
IdentificationBack Directory
[Name]

6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE
[CAS]

94885-04-8
[Synonyms]

C6-Nbd-sm
C6-NBD-SPHINGOMYELIN
NBD C6-SPHINGOMYELIN
FLUORESCENT SPHINGOMYELIN
NBD-C12-L-Threo-sphingosine
C6 NBD Sphingomyelin (d18:1/6:0)
NBD C6-Sphingomyelin DISCONTINUED
N-C6-NBD-SPHINGOSYLPHOSPHORYLCHOLINE
N-HEXANOYL-NBD-SPHINGOSYLPHOSPHORYLCHOLINE
N-Hexanoyl-NBD-D,L-sphingosylphosphorylcholine
N-(NBD-Aminohexanoyl)sphingomyelin semisynthetic from bovine brain
N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecoyl]-L-threo-sphingosine
6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE
N-(N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-epsilon-aminohexanoyl)sphingosylphosphorylcholine
NBD-C12-L-Threo-sphingosine, N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecoyl]-L-threo-sphingosine
N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]HEXANOYL]-SPHINGOSINE-1-PHOSPHOCHOLINE;C6-NBD SPHINGOMYELIN
[(E,2S,3R)-3-hydroxy-2-[6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanoylamino]octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate
N-(NBD-AMINOLAUROYL)-L-THREO-SPHINGOSINE NBD-C12-L-THREO-SPHINGOSINE N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECOYL]-L-THREO-SPHINGOSINE
4-Hydroxy-7-(1-hydroxy-2-hexadecenyl)-N,N,N-trimethyl-14-((7-nitro-4-benzofurazanyl)amino)-9-oxo-3,5-dioxo-8-aza-4-phosphatetradecan-1-aminium hydroxide, inner salt, 4-oxide, (R-(R*,S*-(E)))-
3,5-Dioxo-8-aza-4-phosphatetradecan-1-aminium, 4-hydroxy-7-(1-hydroxy-2-hexadecenyl)-N,N,N-trimethyl-14-((7-nitro-4-benzofurazanyl)amino)-9-oxo-, hydroxide, inner salt, 4-oxide, (R-(R*,S*-(E)))-
[Molecular Formula]

C35H61N6O9P
[MDL Number]

MFCD01074983
[MOL File]

94885-04-8.mol
[Molecular Weight]

740.88
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

Chloroform: Soluble; Ethanol: Soluble; Methanol: Soluble
[form ]

A solid
[color ]

Brown to orange
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

C6 NBD sphingomyelin is a biologically active derivative of sphingomyelin (Item Nos. 22674 | 24345) that is tagged with a fluorescent C6 nitrobenzoxadiazole (C6 NBD; ) group. C6 NBD sphingomyelin has been used to study the metabolism and transport of sphingomyelins. It is degraded in the plasma membrane to C6 NBD ceramide by neutral sphingomyelinase, an enzyme with three-fold higher activity in undifferentiated HT29 cells than in differentiated cells. Unlike endogenous long-chain sphingomyelin and C6 sphingomyelin, C6 NBD sphingomyelin can be transported to the cell surface even in the presence of the vesicular transport inhibitor brefeldin A , but this transport can be blocked by multidrug resistance protein inhibitors in CHO cells. This product is a mixture of the D-erythro and L-threo isomers of sphingomyelin. [Matreya, LLC. Catalog No. 1912]
[Uses]

A probe that fluorescently labels membranous fatty acid phospholipids and has shown to excite the NBD group at 460 nm and emit at 534 nm.
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