| Identification | Back Directory | [Name]
H-ARG-GLY-GLU-SER-OH | [CAS]
93674-97-6 | [Synonyms]
R-G-E-S
rgespeptide
RGES; R-G-E-S
ARG-GLY-GLU-SER
H-ARG-GLY-GLU-SER-OH
[Glu3]-RGES,ControlforRGDPeptides
L-Serine, L-arginylglycyl-L-α-glutamyl-
(4S)-4-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-5-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-5-oxopentanoic acid | [Molecular Formula]
C16H29N7O8 | [MDL Number]
MFCD00076454 | [MOL File]
93674-97-6.mol | [Molecular Weight]
447.45 |
| Hazard Information | Back Directory | [Uses]
Arg-Gly-Glu-Ser is a polypeptide related to RGD and is a negative control for Arg-Gly-Asp-Ser (HY-12290)[1]. | [in vivo]
Arg-Gly-Glu-Ser (5 mg/kg) in combination with LPS or saline + RGDS does not affect neutrophil and macrophage cell numbers and has no effect on protein accumulation compared with LPS- or saline-treated mice, respectively[1]. | [References]
[1] Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18. DOI:10.1186/1465-9921-10-18 |
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