Identification | Back Directory | [Name]
β-N-AcetylglucosaMinidase | [CAS]
9012-33-3 | [Synonyms]
NAG NAGLU MPS3B MPS-IIIB EC 3.2.1.30 EC 3.2.1.52 β-N-acetylhexosaminidase β-N-AcetylglucosaMinidase Acetylglucosaminidase, B2 B-N-ACETYLGLUCOSAMINIDASE P BETA-N-ACETYLHEXOSAMINIDASE Acetylglucosaminidase, beta- BETA-N-ACETYLGLUCOSAMINIDASE Acetylhexosaminidase, .beta.- BETA-N-ACETYLGLUCOSAMINIDASE H N-ACETYL-BETA-D-GLUCOSAMINIDASE Achromopeptidase Lysobacter sp. β1-2,3,4,6-N-Acetylglucosaminidase, BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE Native Human β-N-Acetylglucosaminidase Native Bovine β-N-Acetylglucosaminidase B-N-ACETYLGLUCOSAMINIDASE FROM JACK BEANS B-N-ACETYLGLUCOSAMINIDASE FROM BOVINEKID NEY β-n-acetylglucosaminidase from bovine kidney β-n-acetylglucosaminidase from human placenta B-N-ACETYLGLUCOSAMINIDASEFROM HUMAN PLAC ENTA B-N-ACETYLGLUCOSAMINIDASE AFROM HUMAN PL ACENTA beta-N-Acetylglucosaminidase from bovine kidney B-N-ACETYLGLUCOSAMINIDASE FROMASPERGILLU S NIGER B-N-ACETYLGLUCOSAMINIDASE AFROM PORCINE PLACENTA B-N-ACETYLGLUCOSAMINIDASE, RECOMBINANT, EXPRESSED I β-N-AcetylglucosaminidaseA from bovine epididymis β-N-AcetylglucosaminidaseB from bovine epididymis Native Canavalia ensiformis β-N-Acetylglucosaminidase β-n-acetylglucosaminidase from streptococcus pneumoniae N-ACETYL-BETA-D-GLYCOSAMINIDE-N-ACETYLGLUCOSAMINOHYDROLASE Hexosaminidase 3A from Thermotoga neapolitana, Recombinant beta-N-Acetylglucosaminidase from Streptococcus pneumoniae BETA-N-ACETYLGLUCOSAMINIDASE,JACK BEANS, ~50 U/MG, 500 UG* β-N-Acetylglucosaminidase P preparation from human placenta β-N-Acetylglucosaminidase A preparation from human placenta Hexosaminidase 3C from Saccharophagus degradans, Recombinant β-N-Acetylglucosaminidase A preparation from porcine placenta β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution β-n-acetylglucosaminidase from canavalia ensiformis (jack bean) 2-Acetamido-2-deoxy-β-D-glucoside acetamidodeoxyglucohydrolase BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, STREPTOCOCCUS PNEUMONIAE β-N-Acetylglucosaminidase preparation from Aspergillus niger BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, S. PNEUMONIAE, RECOMBINANT 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSIDE ACETAMIDODEOXYGLUCOHYDROLASE β-N-Acetylhexosaminidase from Streptococcus pyogenes, Recombinant beta-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) β-N-Acetylglucosaminidase from Streptococcus pneumoniae, Recombinant β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase β1-2,3,4,6-N-Acetylglucosaminidase, Streptococcus pneumoniae, Recombinant, E. coli β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean),β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase, β-N-Acetylhexosaminidase | [EINECS(EC#)]
232-730-2 | [Molecular Formula]
NULL | [MDL Number]
MFCD00081402 |
Chemical Properties | Back Directory | [density ]
1.37[at 20℃] | [vapor pressure ]
0.004Pa at 25℃ | [storage temp. ]
2-8°C | [form ]
lyophilized powder | [color ]
Colorless to light yellow | [Water Solubility ]
125g/L at 25℃ | [LogP]
-1.3 at 20℃ |
Hazard Information | Back Directory | [Uses]
Bovine kidney β-N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer′s Disease . | [Uses]
β -N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer’s Disease 1 . Acetylglucosaminidase from Canavalia ensiformis has been used to study enzymic detachment of biofilms. | [Flammability and Explosibility]
Notclassified | [Biochem/physiol Actions]
β-N-Acetylglucosaminidase from Streptococcus pneumoniae is an extracellular glycosidase and has broad specificity over the β1-3 and β1-6 linkages present in mucins. It belongs to the glycoside hydrolase family 85 (GH85). Also called endo-β-N-acetylglucosaminidase, it cleaves at the asparagine residue of the di-N-acetylchitobiose structure in oligosaccharides and acts on fucosylated N-glycan core. Its deglycosylation functionality is exploited in studying functions of glycoproteins. | [Purification Methods]
Purify it by chromatography on DEAD-Biogel, hydroxylapatite chromatography and gel filtration through Sephacryl S200. Two isoforms: a hexosaminidase EI with Km 177WM |
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