| Identification | Back Directory | [Name]
Dimethicone | [CAS]
9006-65-9 | [Synonyms]
KM 9
HL 88
KHS 7
HL 999
Hedrin
D01540
E 1049
DC 1428
DC 1664
DC 5-2117
EY 22-067
DIMETIKON
dimeticone
Polysilane
KF 96A50CS
DC 200-10cS
Dimethicone
Belsil DM 35
DC 100-350CS
DC 200-100cS
Belsil DM 200
Mirasil DM 20
Belsil DM 100
Belsil DM 1000
Clearocast 100
DIMETICONE 350
SILICONE FLUID
DIMETICONUM 350
DIMETHICONE 350
DiMethicone 245
Dow Corning 365
Dow Corning 1413
Dow Corning 1664
Belsil DM 1 Plus
Dow Corning- 664
Dimethicone (nf)
DIMETHICONE 1000
DIMETHYL SILICONE
POLYMETHYLSILOXANE
VISCOSITY STANDARD
Sentry dimethicone
Dow Corning 5-2117
Dow Corning 5-7137
Dow Corning 5-7139
SILICONE OIL DC 200
POLYDIMETHYLSILOXAN
DIMETHICONE COPOLYOL
Dimeticone (jan/inn)
Dow Corning 200/10CST
Dow Corning 200/5 cst
Dow Corning 100-350CS
Vinyl-terminated PDMS
Sentry dimethicone (tn)
POLYDIMETHYLSILOXANE GUM
POLYDIMETHYLSILOXANE 311
dimethicone macromolecule
POLYDIMETHYLSILOXANE 3'320
POLYDIMETHYLSILOXANE 7'100
POLYDIMETHYLSILOXANE 1'850
Dow Corning 200 Fluid 5cSt
POLYDIMETHYLSILOXANE 16'000
POLYDIMETHYLSILOXANE 71'000
POLYDIMETHYLSILOXANE 89'800
POLYDIMETHYLSILOXANE 47'500
POLYDIMETHYLSILOXANE 25'800
POLYDIMETHYLSILOXANE 303'000
POLYDIMETHYLSILOXANE 173'000
POLYDIMETHYLSILOXANE 197'000
POLYDIMETHYLSILOXANE 158'000
Dow Corning 200/100 cSt Fluid
Dow Corning 200 Fluid 350 c/s
DIMETHYLPOLYSILOXANE,TECHNICAL
EIGHT-ARM POLY(DIMETHYL SILOXANE)
SILCOREL(R) ADP1000 ANTIFOAM COMPOUND
REDUCED VOLATILITY POLYDIMETHYLSILOXANE
Dow Corning 365 DiMethicone NF EMulsion
(Methoxy-dimethylsilyl)-trimethylsilane
POLY(DIMETHYLSILOXANE), METHYL TERMINATED
EXTREME LOW VOLATILITY POLYDIMETHYLSILOXANE
DOW CORNING 346 EMULSION SINGLE RELEASE AGENT
Polydimethylsiloxane trimethylsiloxy-terminated
POLYDIMETHYLSILOXANE, BRANCHED, METHYL TERMINATED
Silicone Fluid, High TeMperature Heat Transfer Fluid | [EINECS(EC#)]
-0 | [Molecular Formula]
C6H18OSi2 | [MDL Number]
MFCD00084411 | [MOL File]
9006-65-9.mol | [Molecular Weight]
162.378 |
| Chemical Properties | Back Directory | [Appearance]
colourless to slightly yellow liquid | [density ]
1 g/mL at 20 °C
| [vapor pressure ]
5 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.406
| [Fp ]
121 °C | [storage temp. ]
Refrigerator | [solubility ]
Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, miscible with ethyl acetate, with methyl ethyl ketone and with toluene. | [form ]
neat | [color ]
Colourless | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, organics, acids, alkalis. Corrodes many metals. | [InChI]
InChI=1S/C6H18OSi2/c1-8(2,3)7-9(4,5)6/h1-6H3 | [InChIKey]
UQEAIHBTYFGYIE-UHFFFAOYSA-N | [SMILES]
O([Si](C)(C)C)[Si](C)(C)C | [LogP]
3.646 (est) | [Uses]
dimethicone is a form of silicone used to give products lubricity, slip, and good feel. It can also serve as a formulation defoamer and help reduce the feeling of greasiness that some creams leave on the skin immediately upon application. In addition, dimethicone is reported to protect the skin against moisture loss when used in larger quantities. It improves product flow and spreadability. In combination with other ingredients, dimethicone becomes a good waterproofing material for sunscreen emulsions, and helps reduce the greasiness often seen in high-SPF preparations. | [CAS DataBase Reference]
9006-65-9 | [EPA Substance Registry System]
Dimethicone(9006-65-9) |
| Hazard Information | Back Directory | [Chemical Properties]
colourless to slightly yellow liquid | [Uses]
A silicone oil consisting of a mixture of fully methylated linear siloxane polymers end-blocking with trimethylsiloxy units. Commonly used in skin and hair products. | [Definition]
ChEBI: A polydimethylsiloxane macromolecule, composed of dimethylsiloxane repeating units. | [Indications]
Silicone (dimethicone) ointments are excellent water-protective agents because
they have an extremely low surface tension and penetrate crevices in the skin to
form a plastic-like barrier. Further, they are nontoxic, inert, stable, and water
repellent. As such, they are useful as barrier creams in industry or wherever
constant or frequent exposure to aqueous compounds is a problem. They will
not, however, protect well against solvents, oils, or dusts. | [Production Methods]
Dimethicone isapoly (dimethylsiloxane) obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. The hydrolysis products contain active silanol groups through which condensation polymerization proceeds. By varying the proportions of chlorotrimethylsilane, which acts as a chain terminator, silicones of varying molecular weight may be prepared. Different grades of dimethicone are produced that may be distinguished by a number placed after the name indicating the nominal viscosity. For example, ABIL 20 (Evonik Goldschmidt UK Ltd) has a nominal kinematic viscosity of 18–22mm2/s (18–22cSt).
| [Brand name]
Sentry Dimethicone (Witco); Sentry Dimethicone
Dispension (Witco). | [Pharmaceutical Applications]
Dimethicones of various viscosities are widely used in cosmetic and pharmaceutical formulations. In topical oil-in-water emulsions dimethicone is added to the oil phase as an antifoaming agent. Dimethicone is hydrophobic and is also widely used in topical barrier preparations. Therapeutically, dimethicone may be used with simethicone in oral pharmaceutical formulations used in the treatment of flatulence. Dimethicone is also used to form a waterrepellent film on glass containers. | [Safety]
Dimethicone is generally regarded as a relatively nontoxic and nonirritant material although it can cause temporary irritation to the eyes. In pharmaceutical formulations it may be used in oral and topical preparations. Dimethicones are also used extensively in cosmetic formulations and in certain food applications.
The WHO has set a tentative estimated acceptable daily intake of dimethicone with a relative molecular mass in the range of 200–300 at up to 1.5mg/kg body-weight.
Injection of silicones into tissues may cause granulomatous reactions. Accidental intravascular injection has been associated with fatalities.
| [storage]
Dimethicones should be stored in an airtight container in a cool, dry, place; they are stable to heat and are resistant to most chemical substances although they are affected by strong acids. Thin films of dimethicone may be sterilized by dry heat for at least 2 hours at 160°C. Sterilization of large quantities of dimethicone by steam autoclaving is notrecommended since excesswater diffuses intothe fluid causing it to become hazy. However, thin films may be sterilized by this method. Gamma irradiation may also be used to sterilize dimethicone. Gamma irradiation can, however, cause crosslinking with a consequent increase in the viscosity of fluids. | [Regulatory Status]
Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules and tablets, topical creams,emulsions,lotions,and transdermal preparations).Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
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| Questions And Answer | Back Directory | [Physical and chemical properties]
Dimethyl silicone is also known as methyl silicone oil and polydimethylsiloxane liquid. It appears as colorless transparent viscous liquid, being tasteless, odorless and non-toxic. The molecular formula is CH3 [Si (cH3) 2] nSi (CH3) 3. The average molecular weight is 5000 ~ 100000. Based on the differences on the molecular weight, kinematic viscosity varies from 1.0 × 10-6 ~ 100000 × 10-6 square meters / second. Long-term use temperature range is -50 ~ 180 ℃. In isolated air or inert gas, it can be subject to long-term use at 200 ℃. Viscosity coefficient: 0.31 ~ 0.61. Surface tension: 1.59 ~ 2.15 × 10-4N / cm. Dielectric constant (23 ℃, 100Hz): 2.18 ~ 2.17. Volume resistivity (23 °C): 1.0 × 1014 to 1.0 × 1016Ωcm3. Dielectric loss tangent (23 ℃, 100Hz):0.00002~0.00004. Breakdown voltage strength: 13.7 ~ 17.7kV / mm. It is soluble in benzene, toluene, xylene and ethyl ether, partially soluble in ethanol, butanol and acetone, insoluble in cyclohexanol, methanol, paraffin oil and vegetable oil. It has excellent hydrophobic moisture resistance, good light transmission, and chemical stability. Widely used in insulation, heat, moisture-proof filler, defoamer, mold release agent, lubricant and surface treatment agent. It is produced by the reaction between octamethylcyclotetrasiloxane and hexamethyldisiloxane in the presence of concentrated sulfuric acid or tetramethylammonium hydroxide catalyst.
 | [Toxicity]
It has no obvious acute and chronic poisoning reaction to human beings and mammals, nor be mutagenic and carcinogenic. Oral, inhalation and skin contact have no obvious irritation or allergic reaction to the eyes, skin, and can’t be absorbed by the gastrointestinal tract and skin.
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