Identification | Back Directory | [Name]
Tween 20 | [CAS]
9005-64-5 | [Synonyms]
psml capmul TWEEN 20 Twain 20 FEMA 2915 'TWEEN' 20 emsorb6915 TWEEN(R) 20 TWEEN(R) 21 TWEEN 20(R) TWEEN NO 20 TWEEN(TM) 20 TWEEN(TM) 21 TWEEN-20(TM) hodagpsml-20 liposorbl-20 Tween 20 1LT TWEEN 20PURE Tween\(rg 20 Tween 20  protasorbl-20 armotanpml-20 EMALEX ET-2020 POLYSORBATE 20 POLYSORBATE 21 EmulsifierT-20 glycospersel-20 TWEEN(-1)(R) 20 TWEEN 20 EP, NF POLYSORBATUM 20 emulsifier(t20) dxewmulsepoe-sml glycospersel-20x TWEEN 20 BP GRADE POLYSORBATE,20,NF Polysorbate 20/80 Tween-20(Tween20) POLYSORBATE,20,FCC POLYSORBATE,20(BULK Polysorbate 20, USP SURFACT-AMPS(TM) 20 SORBITAN MONOLAURATE Polysorbate 20 (2 g) Polisorbate 20- PS 20 POLYSORBAT 20, PH EUR Tween20=Polysorbate20 PROTEIN SOLUBILIZER 20 TWEEN(R) 20 POLYSORBATE TWEEN(R) POLYSORBATE 20 sorbimacrogollaurate300 PEG-10 SORBITAN LAURATE PEG-40 SORBITAN LAURATE PEG-44 SORBITAN LAURATE PEG-75 SORBITAN LAURATE PEG-80 SORBITAN LAURATE Tween 20, Ph. Eur. & USP POLYSORBATE 20 extrapure Tween 20, synthesis grade Polysorbate 20 (2 g) (AS) TWEEN(R) 20 250-450 MPA.S Tween(R) 20,Ph. Eur. & USP ZYP-5052 AUTOINDUCTION MEDIA TWEEN 20 CELL CULTURE REAGENT POE (20) SORBITAN MONOLAURATE TWEEN 20 ELECTROPHORESIS GRADE PESTLE AND TUBE 1.5ML ASSORTED TWEEN 20MOLECULAR BIOLOGY GRADE Polysorbatum 20, Tween(R) 20 SURFACTANTS(glyceryl monosterate POLYOXYETHYLENE (20) MONOLAURATE SORBITANPOLYOXYETHYLENEMONOLAURATE TWEEN(R) 20 BIOXTRA, VISCOUS LIQUID POLYOXYETHYLENESORBITAN MONOLAURATE POLYOXYETHYLENE SORBITAN MONOLAUREATE POLYOXYLETHYLENE SORBITAN MONOLAURATE POLYOXYETHYLENE(2)SORBITANMONOLAURATE POLYOXETHYLENE(20)SORBITANMONOLAURATE POLYOXYETHYLENE(6)SORBITANMONOLAURATE Polysorbate 20, Electrophoresis Grade Tween(R) 20 (Polysorbate), NF, Ph Eur Sorbitanmonolaurat, ethoxyliert, 20-EO POLYETHOXYETHANOL SORBITAN MONOLAUREATE POLY(OXYTHEYLENE)N-SORBITAN-MONOLAURATE POLYETHYLENE GLYCOL SORBITAN MONOLAURATE POLYOXYETHYLENE (4) SORBITAN MONOLAURATE POLYOXYETHYLENE(80) SORBITAN MONOLAURAT& Polysorbate 20,Polysorbatum 20, Tween 20 TWEEN(R) 20 Vetec(TM) reagent grade, 40% ACRYL/BIS 37.5:1 PREMIXED PWD ULTRA PURE Tween 20 (Trademark of ICI America, Inc.) Sorbitan monolaureate, ethoxylated (4 EO) POLYOXYETHYLENE (20) SORBITAN MONOLAURATE POLYOXYETHYLENE (80) SORBITAN MONOLAURATE POLYOXYLETHYLENE (20) SORBITAN MONOLAURATE ProteinSolubilizer20,ReadytouseAmpules,Sterile polyoxyethylene sorbitan monolauric acid ester Polyoxyethylene sorbitan monolaurate (Tween 20) Tween20(Polyoxyethylene-20-SorbitanMonolaurate) POLYOXYETHYLENESORBITAN MONOLAURATE*(TWE EN 21) POLYOXYETHYLENESORBITAN MONOLAURATE*SIGM AULTRA Tween 20 (=Polyoxyethylene Sorbitan Monolaurate) polyethylene glycol sorbitan monolaurate solution polyoxyethylene (20)sorbitan monolaurate solution polyoxyethylene (80) sorbitan monolaurate solution POLYOXYETHYLENESORBITAN MONOLAURATE*ELEC TROPHORESIS POLYOXYETHYLENE SORBITAN MONOLAURATE*(TW EEN 20), LO POLYOXYETHYLENESORBITAN MONOLAURATE*CELL CULTURE TE POLYOXYETHYLENESORBITAN MONOLAURATE*MOLE CULAR BIOLO POLYOXYETHYLENE SORBITAN MONOLAURATE*(TW EEN 20), PR Sorbitan,monodadecanoate,poly(oxy-1,2-ethanediyl)derivs. sorbitan,monododecanoate,poly(oxy-1,2-ethanediyl)derivs. sorbitan,monododecanote,poly(oxy-1,2-ethanediyl)derivatives POLYOXYETHYLENE (20) SORBITAN MONOLAURATE SOLUTION, 70% WATER POLYOXYETHYLENE (20) SORBITAN MONOLAURATE SOLUTION, 72 WT.% IN WATER POLYOXYETHYLENE (20) SORBITAN MONOLAURATE SOLUTION, BIOCHEMIKA, ~10% WATER Tween 20 (=Polyoxyethylene Sorbitan Monolaurate) [for Biochemical Research] Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate TWEEN 20,Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate Polyethylene glycol sorbitan monolaurate solution, Polyoxyethylenesorbitan monolaurate TWEEN 20,Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate, Polysorbate 20 | [EINECS(EC#)]
500-018-3 | [Molecular Formula]
C18H34O6 | [MDL Number]
MFCD00165986 | [MOL File]
9005-64-5.mol | [Molecular Weight]
346.46 |
Chemical Properties | Back Directory | [Appearance]
Yellow liquid | [Melting point ]
98.9 °C (decomp) | [Boiling point ]
100 °C
| [density ]
1.11 g/mL at 20 °C
| [vapor pressure ]
<1.4 hPa (20 °C) | [FEMA ]
2915 | [refractive index ]
n20/D 1.468(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
0-6°C | [solubility ]
100 g/L | [form ]
viscous liquid
| [color ]
Amber | [Specific Gravity]
1.090~1.130 (20/20℃) | [Odor]
mild alcohol odor | [PH]
6-8 (50g/l, H2O, 20℃) | [PH Range]
7 | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Odor Type]
alcoholic | [Water Solubility ]
100 g/L | [Hydrophilic-Lipophilic Balance (HLB)]
16.7 | [Uses]
polysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water. | [EPA Substance Registry System]
Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.(9005-64-5) |
Hazard Information | Back Directory | [Chemical Properties]
Yellow liquid | [Definition]
ChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group. | [Preparation]
By condensing the partial esters of sorbitol and its anhydrides with ethylene oxide to effect an oxyethylene copolymerization
at the free hydroxyl groups. | [Brand name]
Tween 20 (ICI Americas). | [General Description]
Polysorbate 20 is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer. | [Health effects]
Polysorbate 20 was a skin irritant in dermatitis patients but was reported not to induce irritant responses when applied to the intact skin of health volunteers. It produced, at worst, minimal irritation in the eyes of rabbits. Only a small number of cases of skin sensitization have been reported in humans, although a moderate to strong sensitizing potential was seen in guinea-pigs treated by intradermal injection. | [Flammability and Explosibility]
Nonflammable |
Questions And Answer | Back Directory | [Description]
Tween 20, whose common commercial names includes Alkest TW 20 and Polysorbate 20, is a mild nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid which is a medium-chain fatty acid found mainly in coconut oil. It is allowed to be used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity.
Tween 20 is widely applied in biological techniques and sciences, which can be added to buffers and reagents for immunohistochemistry, such as Western blots and ELISAs, helping to prevent non-specific antibody binding, decrease background staining and enhance reagent spreading. Besides, Tween 20 also has applications in food production as a common food grade additive which are found in many consumables on the market today. It can also be used as a wetting agent in flavored mouth drops such as Ice Drops, in oral or non-gastrointestinal suspensions and in rubber balers in the elastomer industry.
| [References]
https://en.wikipedia.org/wiki/Polysorbate_20
http://www.organic-creations.com/thickeners-stabilizers/599-polysorbate-20
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