Identification | Back Directory | [Name]
Aspartate aminotransferase | [CAS]
9000-97-9 | [Synonyms]
GOT EC 2.6.1.1 GOT, HUMAN GOT TYPE I GOT, PORCINE GOT TYPE II-A L-TRANSAMINASE EC 2.6.1.1 TYPE I L-ASPARTATE TYPE I L-ASPARTATE TYPE II-A aspartate transaminase L-Transaminase, Broadange Aspartic aminotransferase ASPARTATE AMINOTRANSFERASE Aminotransferase, aspartate N,N-di(glycidyl)-o-toluidine Aspartic acid aminotransferase GLUTAMIC OXALACETIC TRANSAMINASE GLUTAMIC-OXALOACETIC TRANSAMINASE ASPARTATE AMINOTRANSFERASE TYPE I glutamate oxalacetate transamidase GLUTAMATE-OXALOACETATE TRANSAMINASE ASPARTATE AMINOTRANSFERASE TYPE II-A Aspartate aminotransferase USP/EP/BP Aspartate-2-oxoglutarate transaminase 2-OXOGLUTARATE AMINOTRANSFERASE TYPE I GLUTAMIC-OXALACETIC TRANSAMINASE TYPE I Native Human Aspartate Aminotransferase GLUTAMIC-OXALACETIC TRANSAMINASE TYPE II GLUTAMATE OXALOACETIC TRANSAMINASE, HUMAN 2-OXOGLUTARATE AMINOTRANSFERASE TYPE II-A 2-Oxoglutarate-glutamate aminotransferase GLUTAMIC-OXALACETIC TRANSAMINASE TYPE II-A GLUTAMATE OXALOACETATE TRANSAMINASE, HUMAN Aspartate alpha-ketoglutarate transaminase GLUTAMATE OXALOACETIC TRANSAMINASE, PORCINE L-ASPARTATE: 2-OXOGLUTARATE AMINOTRANSFERASE glutamic-oxalacetic transaminase F. porc heart Native Porcine Glutamic-Oxalacetic Transaminase Glutamate Oxaloacetate Transaminase, Porcine Heart Glutamic-Oxalacetic Transaminase from porcine heart GLUTAMIC-OXALACETIC TRANSAMINASE TYPE I FROM PORCIN Aspartate Aminotransferase from E. coli, Recombinant GLUTAMIC OXALACETIC TRANSAMINASE F. PORC HEART, ~1400 U/ML Recombinant Aspartate transaminase from Mycobacterium tuberculosis Glutamicoxalacetictransaminasefromporcineheartsaltfreeabout180unitsmg Glutamic Oxaloacetic Transaminase (GOT) ex. Porcine Heart, 50-300U/mg Solids L-Aspartate:2-oxoglutarate aminotransferase, Aspartate Aminotransferase, GOT | [EINECS(EC#)]
232-571-9 | [Molecular Formula]
C13H17NO2 | [MDL Number]
MFCD00131191 | [MOL File]
9000-97-9.mol | [Molecular Weight]
219.28 |
Hazard Information | Back Directory | [Uses]
Converts L-aspartate and alpha-ketoglutarate to oxaloacetate and L-glutamate | [Definition]
An enzyme that catalyzes reversibly the transfer of an amino group from glutamic acid to oxaloacetic acid, yielding α-ketoglutaric acid and aspartic acid. The codons for aspartate are GAC and GAU. | [General Description]
Glutamic-Oxalacetic Transaminase is found in all tissues and is predominant in the liver and skeletal muscle. It is a prototype of fold-type I pyridoxal 5′-phosphate (PLP)-enzymes. Glutamic-oxalacetic transaminase is a homodimer containing large and small domains in each subunit. | [Biochem/physiol Actions]
Glutamic-oxalacetic transaminase or aspartate aminotransferase (AAT) catalyzes the interconversion of L-aspartate and α-ketoglutarate with oxalacetate and L-glutamate. This reversible transaminase reaction is dependent on pyridoxal 5′-phosphate (PLP). Glutamic-oxalacetic transaminase maintains the nitrogen currency for metabolism by generating L-glutamate. Elevated serum levels of glutamic-oxalacetic transaminase are indicated in myocardial infarction, liver diseases, and some renal diseases. |
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