| Identification | Back Directory | [Name]
3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE | [CAS]
899507-36-9 | [Synonyms]
A 438079
A 438079 HCI
A 438079 HYDROCHLORIDE
3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine
Pyridine, 3-[[5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl]methyl]-
3-{[5-(2,3-DICHLOROPHENYL)-1H-1,2,3,4-TETRAZOL-1-YL]METHYL}PYRIDINE
3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE | [Molecular Formula]
C13H9Cl2N5 | [MDL Number]
MFCD09971142 | [MOL File]
899507-36-9.mol | [Molecular Weight]
306.15 |
| Hazard Information | Back Directory | [Uses]
3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine is a 1-Benzyl-5-aryltetrazole derivative and potential antagonists for the P2X7 receptor. | [Biological Activity]
Competitive P2X 7 receptor antagonist (pIC 50 = 6.9 for the inhibition of Ca 2+ influx in the human recombinant P2X 7 cell line). Devoid of activity at other P2 receptors (IC 50 >> 10 μ M). Possesses antinociceptive activity in models of neuropathic pain in vivo . |
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