| Identification | Back Directory | [Name]
5-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide | [CAS]
885703-64-0 | [Synonyms]
184748
C-FMS-IN-1
c-Fms inhibitor 1
cFmsIN1,c Fms IN 1
5-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
2-Furancarboxamide, 5-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(1-piperidinyl)phenyl]- | [Molecular Formula]
C22H27N5O2 | [MDL Number]
MFCD30533480 | [MOL File]
885703-64-0.mol | [Molecular Weight]
393.48 |
| Chemical Properties | Back Directory | [Boiling point ]
537.6±50.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO : 5 mg/mL (12.71 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
10.49±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
c-Fms-IN-1 is a FMS kinase inhibitor with an IC50 of 0.0008 μM[1].
FMS kinase[1] | [References]
[1]. Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8. |
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