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ChemicalBook--->CAS DataBase List--->875356-43-7

875356-43-7

875356-43-7 Structure

875356-43-7 Structure
IdentificationBack Directory
[Name]

Secukinumab
[CAS]

875356-43-7
[Synonyms]

Secukinuma
Secukinumab/Secukinumab(Hchain)
Hazard InformationBack Directory
[Description]

Secukinumab is currently the first and only fully humanized biological agent that can specifically inhibit interleukin 17A (IL-17A). IL-17A is a core pathogenic factor involved in inflammation and disease progression in psoriasis (PsO), psoriasis arthropathy (PsA) and ankylosing spondylitis (AS), and plays a cornerstone role in the pathogenesis.

[Uses]

Secukinumab is a human interleukin-IL-17A antagonist indicated for the treatment of adults with moderate to severe plaque psoriasis as an alternative to systemic therapy or phototherapy.
[Side effects]

The most common adverse reactions (>1%) with secukinumab were nasopharyngitis, diarrhea, and upper respiratory tract infection.
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