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ChemicalBook--->CAS DataBase List--->873110-21-5

873110-21-5

873110-21-5 Structure

873110-21-5 Structure
IdentificationBack Directory
[Name]

THP-PEG7-OH
[CAS]

873110-21-5
[Synonyms]

THP-PEG7-OH
OH-PEG7-THP
3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-[(tetrahydro-2H-pyran-2-yl)oxy]-
[Molecular Formula]

C19H38O9
[MDL Number]

MFCD29059860
[MOL File]

873110-21-5.mol
[Molecular Weight]

410.5
Hazard InformationBack Directory
[Biological Activity]

THP-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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