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ChemicalBook--->CAS DataBase List--->872141-23-6

872141-23-6

872141-23-6 Structure

872141-23-6 Structure
IdentificationBack Directory
[Name]

WAY-255348
[CAS]

872141-23-6
[Synonyms]

WAY-255348
5-(7-fluoro-3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
[Molecular Formula]

C16H14FN3O
[MDL Number]

MFCD18782604
[MOL File]

872141-23-6.mol
[Molecular Weight]

283.3
Hazard InformationBack Directory
[Description]

WAY-255348 is a potent nonsteroidal progesterone receptor (PR) antagonist. WAY-255348 inhibits the activity of progesterone. WAY-255348 achieves antagonist activity by binding to and subsequently preventing progesterone-induced nuclear accumulation, phosphorylation and promoter interactions of the PR. WAY-255348 bound PR conformation was similar to that of a progesterone agonist-bound PR and distinct from steroidal antagonist-bound PR conformations. WAY-255348 inhibits PR action through a novel molecular mechanism that is distinct from previously studied PR modulators and may be a useful tool to further understanding of PR signaling pathways.
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Website: www.pharmablock.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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