Identification | Back Directory | [Name]
CB-52 | [CAS]
869376-90-9 | [Synonyms]
11-(2-HEXYL-5-HYDROXYPHENOXY)UNDECANOIC ACID CYCLOPROPYLAMIDE | [Molecular Formula]
C26H43NO3 | [MDL Number]
MFCD09951899 | [MOL File]
869376-90-9.mol | [Molecular Weight]
417.62 |
Hazard Information | Back Directory | [Description]
CB-52 is a stable analog of Δ9-tetrahydrocannabinol (THC) and anandamide (AEA). It exhibits high affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 210 and 30 nM, respectively.1 In vitro, CB-52 behaves primarily as a CB1 receptor partial agonist and a CB2 receptor neutral antagonist.2 | [References]
1. Brizzi, A., Brizzi, V., Cascio, M.G., et al. Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors J. Med. Chem. 48,7343-7350(2005). 2. Cascio, M.G., Bisogno, T., Palazzo, E., et al. In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands Br. J. Pharmacol. 149,431-440(2006). |
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