Identification | Back Directory | [Name]
FMoc-NH-8(ethylene glycol)-acetic acid | [CAS]
868594-52-9 | [Synonyms]
Fmoc-NH-PEG8-CH2CO2H FMoc-NH-PEG8-CH2COOH Fmoc-PEG8-acetic acid Fmoc-NH-8(ethylene glycol)-actic acid FMoc-NH-8(ethylene glycol)-acetic acid FMoc-NH-8(ethylene glycol)-acetic acid ISO 9001:2015 REACH 26-[(9-Fluorenylmethoxycarbonyl)amino]-3,6,9,12,15,18,21,24-octaoxahexacosanoic acid 26-(fluoren-9-ylmethyloxycarbonylamino)-3,6,9,12,15,18,21,24-octaoxahexaeicosanoic acid 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester | [Molecular Formula]
C33H47NO12 | [MDL Number]
MFCD27635163 | [MOL File]
868594-52-9.mol | [Molecular Weight]
649.726 |
Chemical Properties | Back Directory | [Boiling point ]
773.7±60.0 °C(Predicted) | [density ]
1.201±0.06 g/cm3(Predicted) | [solubility ]
DMSO : 100 mg/mL (153.91 mM; Need ultrasonic) | [form ]
Oil | [pka]
3.39±0.10(Predicted) | [color ]
Light yellow to brown |
Hazard Information | Back Directory | [Description]
Fmoc-NH-PEG8-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. |
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