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ChemicalBook--->CAS DataBase List--->86541-78-8

86541-78-8

86541-78-8 Structure

86541-78-8 Structure
IdentificationBack Directory
[Name]

BENAZEPRILAT
[CAS]

86541-78-8
[Synonyms]

Cibacen
CGS-14831
BENAZEPRILAT
BENAZEPRILAT HCL HYDRATE
Benazepril Related CoMpound C
BENAZEPRILAT HYDROCHLORIDE HYDRATE
(3S)-3-[[(S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
(3S)-3-[[(1S)-1-carboxy-3-phenylpropyl]aMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine]-1-acetic acid
1H-1-Benzazepine-1-acetic acid, 3-(1S)-1-carboxy-3-phenylpropylamino-2,3,4,5-tetrahydro-2-oxo-, (3S)-
Benazepril Related Compound C (50 mg) ((3S)-3-[[(1S)-1- carboxy-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo- 1H-1-benzazepine]-1-acetic acid)
[Molecular Formula]

C22H24N2O5
[MDL Number]

MFCD00864465
[MOL File]

86541-78-8.mol
[Molecular Weight]

396.44
Chemical PropertiesBack Directory
[Appearance]

Crystalline Solid
[Melting point ]

270-272°C
[alpha ]

D -200.5° (c = 1 in 3% aqueous NH4OH)
[Boiling point ]

711.3±60.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer, Under Inert Atmosphere
[solubility ]

Aqueous Base (Slightly), DMSO (Slightly)
[form ]

Solid
[pka]

2.17±0.10(Predicted)
[color ]

White to Off-White
[CAS DataBase Reference]

86541-78-8
Hazard InformationBack Directory
[Chemical Properties]

Crystalline Solid
[Uses]

A metabolite of Benazepril, which is used as an antihypertensive
[Definition]

ChEBI: A benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino roup of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure.
[storage]

Store at -20°C
Safety DataBack Directory
[HS Code ]

2933790002
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