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ChemicalBook--->CAS DataBase List--->86541-77-7

86541-77-7

86541-77-7 Structure

86541-77-7 Structure
IdentificationBack Directory
[Name]

(1R,3S)-Benazepril Hydrochloride
[CAS]

86541-77-7
[Molecular Formula]

C24H28N2O5 HCl
[MOL File]

86541-77-7.mol
[Molecular Weight]

460.96
Chemical PropertiesBack Directory
[Melting point ]

181-183 °C(Solv: 2-butanone (78-93-3))
Safety DataBack Directory
[HS Code ]

2933790002
Hazard InformationBack Directory
[Uses]

(1R,3S)-Benazepril Hydrochloride is an isomer of Benazepril (B119750), an angiotensin converting enzyme inhibitor and a antihypertensive agent.
[General Description]

Benazepril hydrochloride,(3S)-3-[[(1S)-1-carbethoxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid 3-ethylester hydrochloride (Lotensin), is metabolized rapidly to theactive diacid benazaprilat. As with the ACE prodrugs, nomutagenicity has been found, even though these drugs crossthe placenta.
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