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ChemicalBook--->CAS DataBase List--->865231-46-5

865231-46-5

865231-46-5 Structure

865231-46-5 Structure
IdentificationBack Directory
[Name]

(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid
[CAS]

865231-46-5
[Synonyms]

AMG 837
CS-1283
AMG-837; AMG837
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid
Benzenepropanoic acid, β-1-propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-, (βS)-
(betaS)-beta-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid (AMG-837 free acid) 1259389-38-2 (calium salt hydrate)
[Molecular Formula]

C26H21F3O3
[MDL Number]

MFCD23703041
[MOL File]

865231-46-5.mol
[Molecular Weight]

438.44
Chemical PropertiesBack Directory
[Melting point ]

139-142 °C
[Boiling point ]

565.8±50.0 °C(Predicted)
[density ]

1.251±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

4.20±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

AMG 837 is a potent GPR40 agonist. GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity.
[storage]

Store at -20°C
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