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ChemicalBook--->CAS DataBase List--->858557-69-4

858557-69-4

858557-69-4 Structure

858557-69-4 Structure
IdentificationBack Directory
[Name]

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
[CAS]

858557-69-4
[Synonyms]

MUN57694
26S proteasome inhibitor I
Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
[Molecular Formula]

C23H25N3O4
[MOL File]

858557-69-4.mol
[Molecular Weight]

407.46
Chemical PropertiesBack Directory
[Boiling point ]

621.2±65.0 °C(Predicted)
[density ]

1?+-.0.06 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO : 31.25 mg/mL (76.69 mM; ultrasonic and warming and heat to 60°C)
[form ]

Solid
[pka]

-0.58±0.44(Predicted)
[color ]

White to off-white
Spectrum DetailBack Directory
[Spectrum Detail]

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-(858557-69-4)1HNMR
Hazard InformationBack Directory
[Biological Activity]

20S Proteasome-IN-1 is a 26S proteasome inhibitor extracted from patent WO2006128196A2 compound 2. 20S Proteasome-IN-1 has the potential for cancer, immune-related disorders, inflammation, ischemic conditions, neurodegenerative disorders and other diseases research[1].
[References]

[1]. Parlati F, et, al. Novel substrate for rpn 11 enzymatic activity. WO2006128196A2.
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