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ChemicalBook--->CAS DataBase List--->857036-77-2

857036-77-2

857036-77-2 Structure

857036-77-2 Structure
IdentificationBack Directory
[Name]

Cediranib Maleate
[CAS]

857036-77-2
[Synonyms]

AZD 2171 Maleate
Cediranib Maleate
West to Ni BuMa Maleate
Cediranib Maleate(AZD-2171)
AZD-2171 MALEATE;AZD 2171 MALEATE
Cediranib maleate (AZD-2171 maleate
4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline maleate
[Molecular Formula]

C25H27FN4O3·C4H4O4
[MDL Number]

MFCD27665457
[MOL File]

857036-77-2.mol
[Molecular Weight]

566.59
Chemical PropertiesBack Directory
[Melting point ]

198.3-200.08 °C (polymorph)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:72.5(Max Conc. mg/mL);127.96(Max Conc. mM)
Water:2.0(Max Conc. mg/mL);3.53(Max Conc. mM)
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Cediranib (AZD2171) inhibited VEGF-stimulated proliferation and KDR phosphorylation with IC50 of 0.4 and 0.5 nM, respectively.
[storage]

Store at -20°C
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