| Identification | Back Directory | [Name]
5-BROMO-2,4-DICHLORO-PYRIDINE | [CAS]
849937-96-8 | [Synonyms]
2,4-dichloro-5-bromopyridine
Pyridine, 5-bromo-2,4-dichloro-
5-BROMO-2,4-DICHLORO-PYRIDINE ISO 9001：2015 REACH
5-Bromo-2,4-dichloropyridine5-Bromo-2,4-dichloropyridine | [EINECS(EC#)]
214-589-6 | [Molecular Formula]
C5H2BrCl2N | [MDL Number]
MFCD09031035 | [MOL File]
849937-96-8.mol | [Molecular Weight]
226.89 |
| Chemical Properties | Back Directory | [Melting point ]
21-22℃ | [Boiling point ]
60-62℃ (0.9 Torr) | [density ]
1.848±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
liquid | [pka]
-1.31±0.10(Predicted) | [color ]
Yellow | [InChI]
InChI=1S/C5H2BrCl2N/c6-3-2-9-5(8)1-4(3)7/h1-2H | [InChIKey]
SGCSNJNPPSSPKZ-UHFFFAOYSA-N | [SMILES]
C1(Cl)=NC=C(Br)C(Cl)=C1 |
| Hazard Information | Back Directory | [Synthesis]
5-bromo-2-chloropyridine could be used as a starting material to synthesize 5-Bromo-2,4-dichloropyridine. At -100 °C, diisopropylamine (14 mL, 10 g, 0.10 mol) and 5-bromo-2-chloropyridine (19 g, 0.10 mol) were added consecutively to a solution of butyllithium (0.10 mol) in tetrahydrofuran (0.23 L) and hexanes (60 mL). After 45 min at -100 °C, the mixture was treated with 1,1,2-trichloro-1,2,2-trifluoroethane (12 mL, 19 g, 0.10 mol) and, after 45 min at -75 °C, with water (50 mL). Upon distillation, the product was collected as a colorless liquid, bp 60-62 °C/0.9 mmHg, yield 18.7 g (83%). |
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