Identification | Back Directory | [Name]
Cefteram pivoxil | [CAS]
82547-81-7 | [Synonyms]
T 2588 Tomiron Ro 19-5248 Tomiron 100 CEFTERAMPIVOXYL Cefteram pivoxil Antibiotic T 2588 CefteramPivoxilCefteramPivoxil Pivaloyloxymethyl (Z)-7-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-(5-methyl-2H-tetrazol-2-ylmethyl)- pivaloyloxymethyl (z)-7-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-(5-methyl-2h-tetrazol-2-ylmethyl)-3-cephem-4-carboxylate (6R,7R)-(pivaloyloxy)methyl 7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((5-methyl-2H-tetrazol-2-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0] (6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-3-[(5-Methyl-2H-tetrazol-2-yl)Methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (2,2-DiMethyl-1-oxopropoxy)Methyl Ester 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[6α,7β(Z)]]- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)- | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C22H27N9O7S2 | [MDL Number]
MFCD00941401 | [MOL File]
82547-81-7.mol | [Molecular Weight]
593.64 |
Chemical Properties | Back Directory | [Melting point ]
125-128°C | [density ]
1.3216 (rough estimate) | [refractive index ]
1.7400 (estimate) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO: 0.01 mg/mL (0.02 mM); | [pka]
8.08±0.60(Predicted) | [Water Solubility ]
Water: Insoluble |
Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Yellow Solid | [Uses]
Third generation, orally active cephalosporin antibiotic. Antibacterial. | [Definition]
ChEBI: Cefteram pivoxil is a pivaloyloxymethyl ester, a member of cephams, an oxime O-ether, a member of tetrazoles and a member of 1,3-thiazoles. |
Safety Data | Back Directory | [Toxicity]
LD50 in male, female mice, rats (g/kg): >6.00, 5.86, 5.63, 5.09 i.p.; in both species >6.00 s.c.; in male mice, rats, dogs (g/kg): >6.00, >6.00, >2.00 orally (Sato) |
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