| Identification | Back Directory | [Name]
Azidoacetic acid NHS ester | [CAS]
824426-32-6 | [Synonyms]
NHS-Azide
NHS-Ac-N3
Aeide-C1-NHS ester
Azidoacetic acid NHS ester
(2,5-dioxopyrrolidin-1-yl) 2-azidoacetate
2,5-Pyrrolidinedione, 1-[(azidoacetyl)oxy]-
2-Azidoacetic acid 2,5-dioxo-1-pyrrolidinyl ester
Azidoacetic acid NHS ester,2-Azidoacetic acid 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C6H6N4O4 | [MDL Number]
MFCD24452499 | [MOL File]
824426-32-6.mol | [Molecular Weight]
198.14 |
| Chemical Properties | Back Directory | [Melting point ]
132-133o C | [storage temp. ]
-20°C | [solubility ]
Chloroform (Slightly) | [form ]
powder or crystals | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Azidoacetic acid NHS ester is a compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | [Uses]
Azidoacetic acid NHS ester is a simple azido-containing reagent with an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines at pH 7-9 forming a stable amide bond. The azide allows for chemoselective ligation with an alkyne or cyclooctyne. It is generally used to functionalize amines and amino acids with azidoacetyl groups. It is generally used in click chemistry applications. |
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