| Identification | Back Directory | [Name]
VESNARINONE | [CAS]
81840-15-5 | [Synonyms]
Arkin
CS-2139
OPC 8212
0PC-8212
VESNARINONE
Piteranometozine
Vesnarinone(OPC8212)
VESNARINONE USP/EP/BP
OPC8212;OPC 8212;OPC-8212
3，4-Dihydro-6-[4-(3，4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone
6-[4-(3,4-Dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone
6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one
2(1H)-Quinolinone, 6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro- | [Molecular Formula]
C22H25N3O4 | [MDL Number]
MFCD00867124 | [MOL File]
81840-15-5.mol | [Molecular Weight]
395.45 |
| Chemical Properties | Back Directory | [Melting point ]
238.1-239.5° (Tominaga); mp 238.1-239.8° (Shimizu) | [Boiling point ]
519.41°C (rough estimate) | [density ]
1.2414 (rough estimate) | [refractive index ]
1.6500 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:9.84(Max Conc. mg/mL);24.88(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.26(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);7.59(Max Conc. mM) | [form ]
A crystalline solid | [pka]
2.86(at 25℃) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Vesnarinone is a new orally-active positive inotropic agent introduced for the treatment
of congestive heart failure. It exerts a positive inotropic effect on the heart and has a peripheral vasodilatory effect. Vesnarinone is claimed not to affect heart rate or aggravate
arrhythmia. | [Originator]
Otsuka (Japan) | [Uses]
Cardiotonic. | [Definition]
ChEBI: Arkin (TN) is an organic molecular entity. | [Brand name]
Arkin (Otsuka America);Arkin-Z. |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
|