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ChemicalBook--->CAS DataBase List--->799268-47-6

799268-47-6

799268-47-6 Structure

799268-47-6 Structure
IdentificationBack Directory
[Name]

oMega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aMinooctadec-4-ene-1,3-diol
[CAS]

799268-47-6
[Synonyms]

NBD Sphingosine
oMega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aMinooctadec-4-ene-1,3-diol
4-Heptadecene-1,3-diol, 2-amino-17-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-, (2S,3R,4E)-
OMEGA(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)(2S,3R,4E)-2-AMINOOCTADEC-4-ENE-1,3-DIOL;NBD SPHINGOSINE
[Molecular Formula]

C23H37N5O5
[MDL Number]

MFCD22416765
[MOL File]

799268-47-6.mol
[Molecular Weight]

463.57
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
Hazard InformationBack Directory
[Uses]

NBD Sphingosine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol may be used:
  • as a negative control to determine the binding of Atg12-Atg5 conjugate with phosphatidylethanolamine (PE)-containing liposomes
  • to label sphingosine kinase 1 (SphK1) in order to determine its role in endocytic membrane trafficking
  • to generate 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD)-ceramide C16

[Biological Activity]

Sphingosine serves as a precursor for ceramide. It is involved in the inhibition of protein kinase C in human platelets.
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