Identification | Back Directory | [Name]
Nodinitib-1 | [CAS]
799264-47-4 | [Synonyms]
ML 130 Nodinitib-1 Noditinib-1 CID-1088438 ML-130;ML 130 130 (Nodinitib-1) ML130;CID-1088438 ML130 (Nodinitib-1) Nodinitib-1 USP/EP/BP 1-[(4-Methylphenyl)sulfonyl]-1H-benziMidazol-2-aMine 1H-BenziMidazol-2-aMine, 1-[(4-Methylphenyl)sulfonyl]- 1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-ylamine | [Molecular Formula]
C14H13N3O2S | [MDL Number]
MFCD04322367 | [MOL File]
799264-47-4.mol | [Molecular Weight]
287.34 |
Chemical Properties | Back Directory | [Melting point ]
191-192 °C (decomp) | [Boiling point ]
532.5±43.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMSO: >10mg/mL | [form ]
powder | [pka]
2.55±0.10(Predicted) | [color ]
white to beige |
Hazard Information | Back Directory | [Uses]
Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent. | [Definition]
ChEBI: 1-(4-methylphenyl)sulfonyl-2-benzimidazolamine is a sulfonamide. | [storage]
Store at -20°C |
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