Identification | Back Directory | [Name]
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide | [CAS]
781652-57-1 | [Synonyms]
CDPPB mGluR5 Ligand, CDPPB 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem Benzamide, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)- | [Molecular Formula]
C23H16N4O | [MDL Number]
MFCD12828752 | [MOL File]
781652-57-1.mol | [Molecular Weight]
364.4 |
Hazard Information | Back Directory | [Uses]
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
| [Biochem/physiol Actions]
CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator. | [storage]
Store at -20°C |
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