| Identification | Back Directory | [Name]
(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE | [CAS]
78095-19-9 | [Synonyms]
Hydroxy-DPAT hydrobromide, (R)-(+)-8-
R(+)-8-HYDROXY-DPAT HYDROBROMIDE FULL 5- HT1A SEROTONIN
(R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide
(R) (+) 8 Hydroxy DPAT hydrobromide,(R)(+)8HydroxyDPAT hydrobromide
(R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide | [Molecular Formula]
C16H25NO.BrH | [MDL Number]
MFCD00153810 | [MOL File]
78095-19-9.mol | [Molecular Weight]
328.291 |
| Chemical Properties | Back Directory | [storage temp. ]
protect from light | [solubility ]
H2O: >10mg/mL at ±60°C (with sonication) | [form ]
solid | [color ]
white to off-white | [optical activity]
[α]25/D +68.2°, c = 1 in methanol(lit.) |
| Hazard Information | Back Directory | [Uses]
(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:
- in mice to test the activity of the serotonin receptor
- to test its effect on zebrafish melanocyte migration and survival
- to stimulate hippocampal neurons
| [Biochem/physiol Actions]
(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation. | [storage]
Store at -20°C |
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