| Identification | Back Directory | [Name]
Hirsutine | [CAS]
7729-23-9 | [Synonyms]
16e)-
HIRSUTINE
Methyl (E)-2-[(2
corynan-16-carboxylicacid,16,17-didehydro-17-methoxy-,methylester,(3-bet
18-seco-3-beta-yohimban-16-carboxylicacid,16,17-didehydro-17-methoxy-1met
(3β,16E)-16,17-Didehydro-17-methoxycorynan-16-carboxylic acid methyl ester
(e)-16,17-didehydro-17-methoxy-17,18-seco-3-beta-yohimban-16-carboxylicacid
Methyl (E)-2-[(2S,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[3,2-h]quinolizin-2-yl]-3-methoxyprop-2-enoate
Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αE,2S,3R,12bR)- | [Molecular Formula]
C22H28N2O3 | [MDL Number]
MFCD01750089 | [MOL File]
7729-23-9.mol | [Molecular Weight]
368.47 |
| Chemical Properties | Back Directory | [Melting point ]
101 °C | [Boiling point ]
531.7±50.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
18.13±0.60(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
Hirsutine is a brain penetrant alkaloid from Uncaria rhynchophylla th at exhibit anti-cancercardioprotectiveanti-hypertensiveand anti-arrhythmic activities. It appears th at hirsutine induces apoptosis in lung cancer cells through opening of mitochondrial permeability transition pore (mPTP). Hirsutine exhibit potent anti-dengue virus activity. | [storage]
Store at -20°C |
|
|