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ChemicalBook--->CAS DataBase List--->77-65-6

77-65-6

77-65-6 Structure

77-65-6 Structure
IdentificationBack Directory
[Name]

(2-BROMO-2-ETHYLBUTYRYL)UREA
[CAS]

77-65-6
[Synonyms]

Adalin
Diacid
Hoggar
NYCTAL
URADAL
TILDIN
Nictal
Fydalin
Nenesin
Kartryl
Parkosed
Pelidorm
Bromadel
BROMADAL
CARBROMAL
Adisomnol
Karbromal
NCI-C03805
Pianadalin
PLANADALIN
Dormiturin
Addisomnol
Bromodiacetylurea
Bromacetocarbamide
2-bromo-2-ethylurea
Bromdiethylacetylurea
component of Carbrital
BROMODIETHYLACETYLUREA
1-Bromo-ethyl-butyryl-urea
(2-bromo-ethylbutyryl)-ure
Bromodiethylacetylcarbamide
(2-bromo-2-ethylbutyryl)-ure
UREA,(2-BROMO-ETHYLBUTYRYL)-
(2-BROMO-2-ETHYLBUTYRYL)UREA
2-Brom-2-ethylbutyrylmocovina
N-(2-Bromo-2-ethylbutanoyl)urea
(A-BROMO-A-ETHYLBUTYRYL)CARBAMIDE
alpha-ethyl-alpha-bromobutyrylurea
alpha.-Bromo-alpha-ethylbutyrylurea
(alpha-Bromo-alpha-ethylbutyryl)urea
(alpha-Ethyl-alpha-bromobutyryl)urea
2-bromo-N-carbamoyl-2-ethylbutanamide
2-bromo-N-carbamoyl-2-ethyl-butyramide
(alpha-Bromo-alpha-ethylbutyryl)carbamide
n-(aminocarbonyl)-2-bromo-2-ethyl-butanamid
N-(Aminocarbonyl)-2-bromo-2-ethylbutanamide
n-(aminocarbonyl)-2-bromo-2-ethyl-butanamide
Butanamide, N-(aminocarbonyl)-2-bromo-2-ethyl-
[EINECS(EC#)]

201-046-6
[Molecular Formula]

C7H13BrN2O2
[MDL Number]

MFCD00047872
[MOL File]

77-65-6.mol
[Molecular Weight]

237.09
Chemical PropertiesBack Directory
[Appearance]

white crystalline powder
[Melting point ]

116-119°
[density ]

1.5528 (rough estimate)
[refractive index ]

1.5140 (estimate)
[Stability:]

Stable. Combustible. Incompatible with acids, alkalies, strong oxidizing agents.
[Water Solubility ]

0.5g/L(20 ºC)
[EPA Substance Registry System]

Carbromal (77-65-6)
Hazard InformationBack Directory
[Chemical Properties]

white crystalline powder
[General Description]

Odorless tasteless white crystalline powder. Saturated solution in water neutral to litmus.
[Air & Water Reactions]

May be sensitive to prolonged exposure to air and light. Insoluble in water.
[Reactivity Profile]

The neat material may be sensitive to prolonged exposure to air and light. (2-BROMO-2-ETHYLBUTYRYL)UREA is incompatible with acids and alkalis.
[Fire Hazard]

Flash point data for (2-BROMO-2-ETHYLBUTYRYL)UREA are not available; however, (2-BROMO-2-ETHYLBUTYRYL)UREA is probably combustible.
[Originator]

Antineuralgiae,Jelfa
[Definition]

ChEBI: Carbromal is a N-acylurea.
[Manufacturing Process]

120 parts urea and 258 parts 2-bromo-2-ethylbutyrylbromide was mixed and stood at room temperature for 12 hours; then the mixture was heated about 3 hours on water bath and adjusted to alkaline pH with sodium bicarbonate after cooling. The unreacted products was dissolved in brine, the insoluble part was filtered off. The recrystallization from ethanol gave the title product - (2-bromo-2-ethyl-butyryl)urea as the colorless, odorless crystals. MP 114°- 118°C.
[Brand name]

Adalin (Sterling Winthrop).
[Therapeutic Function]

Hypnotic, Sedative
Safety DataBack Directory
[Safety Profile]

Poison by ingestion, subcutaneous, and possibly other routes. Moderately toxic via intravenous and intraperitoneal routes. Mutation data reported. A sedative, hypnotic, and central Intdious system depressant. When heated to decomposition it emits very toxic fumes of NOx and Br-.
[Hazardous Substances Data]

77-65-6(Hazardous Substances Data)
[Toxicity]

LD50 oral in rat: 316mg/kg
Spectrum DetailBack Directory
[Spectrum Detail]

(2-BROMO-2-ETHYLBUTYRYL)UREA(77-65-6)MS
(2-BROMO-2-ETHYLBUTYRYL)UREA(77-65-6)IR1
(2-BROMO-2-ETHYLBUTYRYL)UREA(77-65-6)IR2
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