| Identification | Back Directory | [Name]
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE | [CAS]
7665-99-8 | [Synonyms]
CGMP
3:5-CGMP
cyclicgmp
3',5'-CGMP
3',5'-cGMPH
3',5'-cyclic GMP
cGMP, cyclic GMP
Cyclic 3',5'-guanylic acid
Cyclic guanosine phosphate
Guanosine 3',5'-Monophosphate
Guanosine 3',5'-phosphoric acid
Guanosine 3′,5′-phosphate (cyclic)
Guanosine cyclic 3',5'-monophosphate
3',5'-Cyclic guanosine Monophosphate
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
GUANOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID
GUANOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID
CGMP, GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE
Guanosine 3′,5′-cyclic monophosphate(CGMP)
guanosine cyclic 3',5'-(hydrogen phosphate)
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE USP/EP/BP
guanosine 3':5'-cyclic monophosphate*free acid
GUANOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID FREE ACID
Guanosine 3′,5′-cyclic monophosphate,cGMP, cyclic GMP
2-amino-9-[(1R,6R,8R,9R)-3,9-dihydroxy-3-oxo-2,4,7-trioxa-3,lambda5-phosphabicyclo[4.3.0]non-8-yl]-3H-purin-6-one | [EINECS(EC#)]
231-641-6 | [Molecular Formula]
C10H12N5O7P | [MDL Number]
MFCD00070129 | [MOL File]
7665-99-8.mol | [Molecular Weight]
345.21 |
| Chemical Properties | Back Directory | [Melting point ]
>242°C (dec.) | [density ]
2?+-.0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
1% sodium bicarbonate: 50 mg/mL | [form ]
powder | [pka]
1.03±0.60(Predicted) | [color ]
white | [Stability:]
Hygroscopic |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
22-26-36 | [WGK Germany ]
3 | [HS Code ]
29349990 | [Toxicity]
The product
formed by the guanylate cyclase enzymes from GTP. It is
a cellular “second messenger,” participating in the regulation
of many intracellular events. Toxicants (e.g., nitroprusside)
may cause physiological changes by interfering with aspects of cyclic GMP metabolism. |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Guanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation. | [Definition]
ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP. | [Biochem/physiol Actions]
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG). |
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