| Identification | Back Directory | [Name]
FMoc-NH-PEG12-CH2CH2COOH | [CAS]
756526-01-9 | [Synonyms]
Fmoc-N-amido-PEG12-Acid
Fmoc-N-amido-PEG24-acid
Fmoc-N-amido-PEG13-acid
FMoc-NH-PEG12-CH2CH2COOH
Fmoc-NH-PEG36-CH2CH2COOH
Fmoc-PEG12-propionic acid
O-(N-FMoc-2-aMinoethyl)-O'-(2-carboxyethyl)-undecathyleneglycol
O-(N-Fmoc-2-aminoethyl)-O'-(2-carboxyethyl)undecaethyleneglycol≥ 97% (HPLC)
Poly(oxy-1,2-ethanediyl), -(2-carboxyethyl)--[2-[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]- | [Molecular Formula]
C42H65NO16 | [MDL Number]
MFCD08064302 | [MOL File]
756526-01-9.mol | [Molecular Weight]
839.963 |
| Questions and Answers (Q&A) | Back Directory | [Description]
Fmoc-NH-PEG12-CH2CH2COOH (also known as Fmoc-NH-PEG12-propionic acid) is a protected form of propionic acid modified with Fmoc (9-FLUORENYLME- THOXYCARBONYL) and PEG12 (polyethylene glycol 12). It is useful in the peptide synthesis and biomolecules synthesis. For example, it can be used for tether peptides to proteins or other large biomolecules (such as nucleic acids). The attachment of the hydrophobic peptide, NH2-PEG12 can effectively reduce aggregation.
| [References]
https://www.aapptec.com/fmocnhpeg12propionic-acid-i-396.html
Strømgaard, Kristian, A. Bach, and K. B. Nissen. "FATTY ACID DERIVATIVES OF DIMERIC INHIBITORS OF PSD-95.", WO/2015/078477. 2015.
Masayasu Kuwahara, et al. "Synthesis of oxy-peptide nucleic acids with mixed sequences." Nucleic acids symposium series 42.42(1999):31.
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