| Identification | Back Directory | [Name]
TRIPTOPHENOLIDE | [CAS]
74285-86-2 | [Synonyms]
HYPOLIDE
TRIPTOPHENOLIDE
Triptophenolide, BR
Triptophenolide (Hypolide
Hypolide (Triptophenolide)
Triptophenolide, 98%, from Tripterygium wilfordii Hook.f.
6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one
6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e]isobenzofuran-1-one
(3bR,9bS)-3b,4,5,9b,10,11-Hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)phenanthro[1,2-c]furan-1(3H)-one
Phenanthro[1,2-c]furan-1(3H)-one, 3b,4,5,9b,10,11-hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)-, (3bR,9bS)- | [Molecular Formula]
C20H24O3 | [MDL Number]
MFCD00210567 | [MOL File]
74285-86-2.mol | [Molecular Weight]
312.4 |
| Chemical Properties | Back Directory | [Melting point ]
232-233℃ | [Boiling point ]
490.0±45.0 °C(Predicted) | [density ]
1.21 | [solubility ]
DMSO : 100 mg/mL (320.10 mM; Need ultrasonic) | [form ]
powder | [pka]
10.63±0.40(Predicted) | [color ]
Yellowish |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Begonia, Tripterygium root bark. | [Uses]
Used for content determination/identification/pharmacological experiments, etc. | [Definition]
ChEBI: (3bR,9bS)-6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e]isobenzofuran-1-one is an oxo steroid. | [Biological Activity]
Triptophenolide is a colorless crystal isolated from the ethyl acetate extraction site of Tripterygium wilfordii. | [target]
| Target | Value | AR-WT
() | 260 nM | AR -T877A
() | 388 nM | AR-F876L
() | 480 nM |
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