Identification | Back Directory | [Name]
1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester | [CAS]
723304-76-5 | [Synonyms]
CCR8 antagonist 1 1-Piperidinecarboxylic acid, 4-[[[4-[(2-methylbenzoyl)amino]-1-naphthalenyl]sulfonyl]amino]-, ethyl ester | [Molecular Formula]
C26H29N3O5S | [MOL File]
723304-76-5.mol | [Molecular Weight]
495.59 |
Chemical Properties | Back Directory | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 25 mg/mL (50.44 mM; Need ultrasonic) | [form ]
Solid | [pka]
11.41±0.20(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Biological Activity]
CCR8 antagonist 1 (compound 15) is a potente human CCR8 antagonist with a Ki of 1.6 nM[1]. | [References]
[1]. Jenkins TJ, et al. Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem. 2007;50(3):566-584. |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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