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ChemicalBook--->CAS DataBase List--->7054-25-3

7054-25-3

7054-25-3 Structure

7054-25-3 Structure
IdentificationBack Directory
[Name]

QUINIDINE GLUCONATE
[CAS]

7054-25-3
[Synonyms]

QUINIDINE GLUCONATE
quinidine D-gluconate
QUINIDINEGLUCONATE,USP
QUINIDINE GLUCONATE SALT
XHKUDCCTVQUHJQ-RNVKORQYSA-N
Quinidine Gluconate (200 mg)
QUINIDINE GLUCONATE USP/EP/BP
Quinidine Gluconate (1595000)
quinidinemono-d-gluconate(salt)
compd.withquinidine(1:1),d-gluconicaci
d-gluconicacid,compd.with(9s)-6’-methoxycinchonan-9-ol(1:1)
6’-methoxy-cinchonan-9-o(9s)-cinchonan-9-omono-d-gluconate(salt)
[EINECS(EC#)]

230-333-9
[Molecular Formula]

C26H36N2O9
[MDL Number]

MFCD00067566
[MOL File]

7054-25-3.mol
[Molecular Weight]

520.57
Chemical PropertiesBack Directory
[Melting point ]

175-176 C
[form ]

neat
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

20/21/22-36/37/38
[Safety Statements ]

36-26
[RIDADR ]

1544
[WGK Germany ]

3
[RTECS ]

LZ5250000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[HS Code ]

2939200050
Hazard InformationBack Directory
[Uses]

Cardiac depressant (anti-arrhythmic).
[Uses]

Quinidine Gluconate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
[Definition]

ChEBI: Quinidine D-gluconate is a D-gluconate adduct. It is functionally related to a quinidine.
[Brand name]

Duraquin (Warner Chilcott); Quinaglute (Berlex).
[General Description]

Quinidinium gluconate(Duraquin, Quinaglute) occurs as an odorless, very bitter,white powder. In contrast with the sulfate salt, it is freelysoluble in water. This is important because there are emergencieswhen the condition of the patient and the need for arapid response make the oral route of administration inappropriate.The high water solubility of the gluconate saltalong with a low irritant potential makes it valuable when aninjectable form is needed in these emergencies. Quinidinegluconate forms a stable aqueous solution. When used for injection, it usually contains 80 mg/mL, equivalent to 50 mgof quinidine or 60 mg of quinidine sulfate.
[Veterinary Drugs and Treatments]

Quinidine is used in small animal or equine medicine for the treatment of ventricular arrhythmias (VPCs, ventricular tachycardia), refractory supraventricular tachycardias, and supraventricular arrhythmias associated with anomalous conduction in Wolff- Parkinson-White (WPW) syndrome. Chronic use of quinidine for controlling ventricular arrhythmias and supraventricular tachycardia in dogs has diminished over the years as other drugs appear to be more effective. It is still used in dogs and horses to convert atrial fibrillation to sinus rhythm. Oral therapy is generally not used in cats.
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