Identification | Back Directory | [Name]
(+/-)-8-PRENYLNARINGENIN | [CAS]
68682-02-0 | [Synonyms]
rac 8-Prenylnaringenin (+/-)-8-PRENYLNARINGENIN Naringenin 8-Prenyl Racemate 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-buten-1-yl)-4H-1-benzopyran-4-one (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-butenyl)-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)- | [EINECS(EC#)]
245-096-7 | [Molecular Formula]
C20H20O5 | [MDL Number]
MFCD21364781 | [MOL File]
68682-02-0.mol | [Molecular Weight]
340.37 |
Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Light yellow powder | [color ]
Off-White to Pale Yellow | [Stability:]
Light Sensitive |
Hazard Information | Back Directory | [Description]
(±)-8-Prenylnaringenin ((±)-8-PN) is a prenylflavonoid with potent estrogenic activity that can be isolated from hops. It inhibits both isoforms of the human estrogen receptor (ER; IC50s = 57 and 68 nM for ERα and ERβ, respectively). (±)-8-PN is effective in vivo, suppressing loss of bone mineral density in ovariectomized rats and blocking changes in tail skin temperature in a rat model of postmenopausal hot flashes. | [Uses]
8-Prenylnaringenin is a prenylflavonoid, a class on non-steroidal phytoestrogen that mimicks and/or modulating endogenous estrogens via estrogen receptor binding. | [Definition]
ChEBI: Rac 8-Prenylnaringenin is a member of flavanones. |
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Energy Chemical
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