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ChemicalBook--->CAS DataBase List--->682745-41-1

682745-41-1

682745-41-1 Structure

682745-41-1 Structure
IdentificationBack Directory
[Name]

Tivozanib
[CAS]

682745-41-1
[Synonyms]

Tivozanib hydrochloride
Tivozanib hydrochloride hydrate
1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea
N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-urea monohydrochloride monohydrate
[Molecular Formula]

C22H22Cl2N4O6
[MDL Number]

MFCD34184484
[MOL File]

682745-41-1.mol
[Molecular Weight]

509.34
Chemical PropertiesBack Directory
[storage temp. ]

4°C, away from moisture and light
[solubility ]

DMSO : 250 mg/mL (490.83 mM; Need ultrasonic)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Tivozanib also known as AV-951 is an orally bioavailable potent VEGFR-1, 2 and 3, c-Kit and PDGFR inhibitor with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM, respectively.
[storage]

4°C, away from moisture and light
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