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ChemicalBook--->CAS DataBase List--->676326-36-6

676326-36-6

676326-36-6 Structure

676326-36-6 Structure
IdentificationBack Directory
[Name]

Methyl 1-acetyl-2-oxoindoline-6-carboxylate
[CAS]

676326-36-6
[Synonyms]

Nintedanib-002
methyl-1-acetyl2-oxoindole-6-carboxylate
Methyl 1-acetyl-2-oxoindoline-6-carboxylate
methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate
Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
TIANFU-CHEM - Methyl 1-acetyl-2-oxoindoline-6-carboxylate
1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methy...
Nintedanib impurity 1/Methyl 1-Acetyl-2-oxoindoline-6-carboxylate
1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester
1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
1H-Indole-6-carboxylic acid, 1-acetyl-2,3-dihydro-2-oxo-, methyl ester
[Molecular Formula]

C12H11NO4
[MDL Number]

MFCD18251630
[MOL File]

676326-36-6.mol
[Molecular Weight]

233.22
Chemical PropertiesBack Directory
[Boiling point ]

489.5±45.0 °C(Predicted)
[density ]

1.330
[pka]

-1.94±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
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