| Identification | Back Directory | [Name]
(5alpha,8alpha,9alpha)-5,8,9,10-tetrahydro-5,9-methanobenzocycloocten-8-ylammonium chloride | [CAS]
67384-25-2 | [Synonyms]
Org-6906 free
(5alpha,8alpha,9alpha)-5,8,9,10-tetrahydro-5,9-methanobenzocycloocten-8-ylammonium chloride | [EINECS(EC#)]
266-675-0 | [Molecular Formula]
C13H16ClN | [MDL Number]
MFCD32182626 | [MOL File]
67384-25-2.mol | [Molecular Weight]
221.726 |
| Hazard Information | Back Directory | [Description]
Org-6906 is a dual of monoamine uptake inhibitor and α2 adrenoceptor antagonist potentially for the treatment. Org-6906 facilitated potassium-stimulated release of noradrenaline from slices of cortex, displaced [3H]rauwolscine and [3H]dihydroergocryptine from their binding sites but only weakly blocked alpha 1-adrenoceptors. The alpha 2-adrenolytic properties were also apparent in behavioural interaction models. The compound antagonized the sleep-inducing effects of clonidine in chicks and mice and it antagonized the mydriasis induced by clonidine in the rat. |
|
|